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1

The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome

Sebaihia, Mohammed, Wren, Brendan W, Mullany, Peter, Fairweather, Neil F, Minton, Nigel, Stabler, Richard, Thomson, Nicholas R, Roberts, Adam P, Cerdeño-Tárraga, Ana M, Wang, Hongmei

Journal:

Nature Genetics

Year:

2006

Language:

english

File:

PDF, 617 KB

english, 2006

2

Characterization of the lipopolysaccharide of Yersinia pestis

Joann L. Prior, Paul G. Hitchen, Diane E. Williamson, Andrew J. Reason, Howard R. Morris, Anne Dell, Brendan W. Wren, Richard W. Titball

Journal:

Microbial Pathogenesis

Year:

2001

Language:

english

File:

PDF, 139 KB

english, 2001

3

The identification of two protective DNA vaccines from a panel of five plasmid constructs encoding Brucella melitensis 16M genes

Nicola J. Commander, Stephen A. Spencer, Brendan W. Wren, Alastair P. MacMillan

Journal:

Year:

2007

Language:

english

File:

PDF, 174 KB

english, 2007

4

Campylobacter – a tale of two protein glycosylation systems

Christine M. Szymanski, Susan M. Logan, Dennis Linton, Brendan W. Wren

Journal:

Trends in Microbiology

Year:

2003

Language:

english

File:

PDF, 144 KB

english, 2003

5

Plague: the mysterious past and terrifying future of the world's most dangerous disease

Journal:

Journal of Clinical Investigation

Year:

2005

Language:

english

File:

PDF, 61 KB

english, 2005

6

'Add, stir and reduce': Yersinia spp. as model bacteria for pathogen evolution

McNally, Alan, Thomson, Nicholas R., Reuter, Sandra, Wren, Brendan W.

Journal:

Nature Reviews Microbiology

Year:

2016

Language:

english

File:

PDF, 1.39 MB

english, 2016

7

Production and efficacy of a low-cost recombinant pneumococcal protein polysaccharide conjugate vaccine

Herbert, Jenny A., Kay, Emily J., Faustini, Sian E., Richter, Alex, Abouelhadid, Sherif, Cuccui, Jon, Wren, Brendan, Mitchell, Timothy J.

Journal:

Year:

2018

Language:

english

File:

PDF, 1.62 MB

english, 2018

8

Recent advances in the production of recombinant glycoconjugate vaccines

Kay, Emily, Cuccui, Jon, Wren, Brendan W.

Journal:

Year:

2019

Language:

english

File:

PDF, 1.07 MB

english, 2019

9

Improving protein glycan coupling technology (PGCT) for glycoconjugate vaccine production

Dow, Jennifer Mhairi, Mauri, Marta, Scott, Timothy Alexander, Wren, Brendan William

Journal:

Expert Review of Vaccines

Year:

2020

File:

PDF, 2.23 MB

2020

10

Microarrays for bacterial pathogens—hope or hype?

Brendan W. Wren

Journal:

Comparative and Functional Genomics

Year:

2002

Language:

english

File:

PDF, 57 KB

english, 2002

11

Microarray analysis of Campylobacter jejuni: to the guts of the problem!

Nick Dorrell, Olivia L. Champion, Brendan W. Wren

Journal:

Comparative and Functional Genomics

Year:

2002

Language:

english

File:

PDF, 70 KB

english, 2002

12

The Campylobacter jejuni glycome

Andrey V. Karlyshev, Julian M. Ketley, Brendan W. Wren

Journal:

FEMS Microbiology Reviews

Year:

2005

Language:

english

File:

PDF, 586 KB

english, 2005

13

Clostridium difficile—A continually evolving and problematic pathogen

Lisa F. Dawson, Esmeralda Valiente, Brendan W. Wren

Journal:

Infection, Genetics and Evolution

Year:

2009

Language:

english

File:

PDF, 306 KB

english, 2009

14

Campylobacter jejuni-mediated disease pathogenesis: an update

Matthias Zilbauer, Nick Dorrell, Brendan W. Wren, Mona Bajaj-Elliott

Journal:

Transactions of the Royal Society of Tropical Medicine and Hygiene

Year:

2008

Language:

english

File:

PDF, 216 KB

english, 2008

15

Burkholderia pseudomallei: animal models of infection

Richard W. Titball, Paul Russell, Jon Cuccui, Anna Easton, Ashraful Haque, Tim Atkins, Mitali Sarkar-Tyson, Vicki Harley, Brendan Wren, Gregory J. Bancroft

Journal:

Transactions of the Royal Society of Tropical Medicine and Hygiene

Year:

2008

Language:

english

File:

PDF, 191 KB

english, 2008

16

Helicobacter pylori vaccine strategies – triggering a gut reaction

W.John W Morrow, Caterina Hatzifoti, Brendan W Wren

Journal:

Immunology Today

Year:

2000

Language:

english

File:

PDF, 72 KB

english, 2000

17

The HtrA family of serine proteases

Mark J. Pallen, Brendan W. Wren

Journal:

Molecular Microbiology

Year:

1997

Language:

english

File:

PDF, 1.10 MB

english, 1997

18

‘Going wrong with confidence’: misleading sequence analyses of CiaB and ClpX

Mark Pallen, Brendan Wren, Julian Parkhill

Journal:

Molecular Microbiology

Year:

1999

Language:

english

File:

PDF, 33 KB

english, 1999

19

Genetic and biochemical evidence of a Campylobacter jejuni capsular polysaccharide that accounts for Penner serotype specificity

Andrey V. Karlyshev, Dennis Linton, Norman A. Gregson, Albert J. Lastovica, Brendan W. Wren

Journal:

Molecular Microbiology

Year:

2000

Language:

english

File:

PDF, 446 KB

english, 2000

20

Multiple N-acetyl neuraminic acid synthetase (neuB) genes in Campylobacter jejuni: identification and characterization of the gene involved in sialylation of lipo-oligosaccharide

Dennis Linton, Andrey V. Karlyshev, Paul G. Hitchen, Howard R. Morris, Anne Dell, Norman A. Gregson, Brendan W. Wren

Journal:

Molecular Microbiology

Year:

2000

Language:

english

File:

PDF, 475 KB

english, 2000

21

Phase variation of a β-1,3 galactosyltransferase involved in generation of the ganglioside GM1-like lipo-oligosaccharide of Campylobacter jejuni

Dennis Linton, Michel Gilbert, Paul G. Hitchen, Anne Dell, Howard R. Morris, Warren W. Wakarchuk, Norman A. Gregson, Brendan W. Wren

Journal:

Molecular Microbiology

Year:

2000

Language:

english

File:

PDF, 679 KB

english, 2000

22

Molecular characterization of the surface layer proteins from Clostridium difficile

Emanuela Calabi, Steven Ward, Brendan Wren, Thanai Paxton, Maria Panico, Howard Morris, Anne Dell, Gordon Dougan, Neil Fairweather

Journal:

Molecular Microbiology

Year:

2001

Language:

english

File:

PDF, 328 KB

english, 2001

23

Identification of N-acetylgalactosamine-containing glycoproteins PEB3 and CgpA in Campylobacter jejuni

Dennis Linton, Elaine Allan, Andrey V. Karlyshev, Andrew D. Cronshaw, Brendan W. Wren

Journal:

Molecular Microbiology

Year:

2002

Language:

english

File:

PDF, 615 KB

english, 2002

24

Structural characterization of lipo-oligosaccharide (LOS) from Yersinia pestis: regulation of LOS structure by the PhoPQ system

Paul G. Hitchen, Joann L. Prior, Petra C. F. Oyston, Maria Panico, Brendan W. Wren, Richard W. Titball, Howard R. Morris, Anne Dell

Journal:

Molecular Microbiology

Year:

2002

Language:

english

File:

PDF, 1.25 MB

english, 2002

25

Identification and characterisation of a novel adhesin Ifp inYersinia pseudotuberculosis

Philippa CR Strong, Stewart J Hinchliffe, Hannah Patrick, Steve Atkinson, Olivia L Champion, Brendan W Wren

Journal:

BMC Microbiology

Year:

2011

Language:

english

File:

PDF, 7.44 MB

english, 2011

26

The analysis ofpara-cresol production and tolerance inClostridium difficile027 and 012 strains

Lisa F Dawson, Elizabeth H Donahue, Stephen T Cartman, Richard H Barton, Jake Bundy, Ruth McNerney, Nigel P Minton, Brendan W Wren

Journal:

BMC Microbiology

Year:

2011

Language:

english

File:

PDF, 1.31 MB

english, 2011

27

Liposomal delivery of p-ialBand p-omp25DNA vaccines improves immunogenicity but fails to provide full protection againstB. melitensischallenge

Nicola J Commander, James M Brewer, Brendan W Wren, Stephen A Spencer, Alastair P MacMillan, Judith A Stack

Journal:

Genetic Vaccines and Therapy

Year:

2010

Language:

english

File:

PDF, 430 KB

english, 2010

28

Evidence ofYersinia pestisDNA from fleas in an endemic plague area of Zambia

Bernard M Hang’ombe, Ichiro Nakamura, Kenny L Samui, Davy Kaile, Aaron S Mweene, Bukheti S Kilonzo, Hirofumi Sawa, Chihiro Sugimoto, Brendan W Wren

Journal:

BMC Research Notes

Year:

2012

Language:

english

File:

PDF, 350 KB

english, 2012

29

Functional analysis of the Campylobacter jejuni N-linked protein glycosylation pathway

Dennis Linton, Nick Dorrell, Paul G. Hitchen, Saba Amber, Andrey V. Karlyshev, Howard R. Morris, Anne Dell, Miguel A. Valvano, Markus Aebi, Brendan W. Wren

Journal:

Molecular Microbiology

Year:

2005

Language:

english

File:

PDF, 516 KB

english, 2005

30

The RovA regulons of Yersinia enterocolitica and Yersinia pestis are distinct: evidence that many RovA-regulated genes were acquired more recently than the core genome

Jason S. Cathelyn, Damon W. Ellison, Stewart J. Hinchliffe, Brendan W. Wren, Virginia L. Miller

Journal:

Molecular Microbiology

Year:

2007

Language:

english

File:

PDF, 350 KB

english, 2007

31

A major role for intestinal epithelial nucleotide oligomerization domain 1 (NOD1) in eliciting host bactericidal immune responses to Campylobacter jejuni

Matthias Zilbauer, Nick Dorrell, Abdi Elmi, Keith J. Lindley, Stephanie Schüller, Hannah E. Jones, Nigel J. Klein, Gabriel Núňez, Brendan W. Wren, Mona Bajaj-Elliott

Journal:

Cellular Microbiology

Year:

2007

Language:

english

File:

PDF, 560 KB

english, 2007

32

A major role for intestinal epithelial nucleotide oligomerization domain 1 (NOD1) in eliciting host bactericidal immune responses to Campylobacter jejuni

Matthias Zilbauer, Nick Dorrell, Abdi Elmi, Keith J. Lindley, Stephanie Schüller, Hannah E. Jones, Nigel J. Klein, Gabriel Núňez, Brendan W. Wren, Mona Bajaj-Elliott

Journal:

Cellular Microbiology

Year:

2007

Language:

english

File:

PDF, 24 KB

english, 2007

33

Identification and molecular cloning of a 70 kDa species-specific antigen common to Clostridium difficile

Brendan W. Wren, Peter P. Mullany, Christopher L. Clayton, Soad Tabaqchali

Journal:

FEMS Microbiology Letters

Year:

1988

Language:

english

File:

PDF, 891 KB

english, 1988

34

Nucleotide sequence of Clostridium difficile toxin A gene fragment and detection of toxigenic strains by polymerase chain reaction

Brendan W. Wren, Christopher L. Clayton, Soad Tabaqchali

Journal:

FEMS Microbiology Letters

Year:

1990

Language:

english

File:

PDF, 512 KB

english, 1990

35

Degenerate PCR primers for the amplification of fragments from genes encoding response regulators from a range of pathogenic bacteria

Brendan W. Wren, Susan M. Colby, Rachel R. Cubberley, Mark J. Pallen

Journal:

FEMS Microbiology Letters

Year:

1992

Language:

english

File:

PDF, 431 KB

english, 1992

36

A flagellar-specific ATPase (FliI) is necessary for flagellar export in Helicobacter pylori

Peter J Jenks, Susan Foynes, Stephen J Ward, Chrystala Constantinidou, Charles W Penn, Brendan W Wren

Journal:

FEMS Microbiology Letters

Year:

1997

Language:

english

File:

PDF, 611 KB

english, 1997

37

Identification, cloning and initial characterisation of FeuPQ in Brucella suis: a new sub-family of two-component regulatory systems

Nick Dorrell, Steve Spencer, Vincent Foulonge, Patricia Guigue-Talet, David O'Callaghan, Brendan W Wren

Journal:

FEMS Microbiology Letters

Year:

1998

Language:

english

File:

PDF, 311 KB

english, 1998

38

Functional analysis of the roles of FliQ and FlhB in flagellar expression in Helicobacter pylori

Susan Foynes, Nick Dorrell, Stephen J Ward, Zun W Zhang, Andy A McColm, Mike J.G Farthing, Brendan W Wren

Journal:

FEMS Microbiology Letters

Year:

1999

Language:

english

File:

PDF, 270 KB

english, 1999

39

Investigation into the role of the serine protease HtrA in Yersinia pestis pathogenesis

Kerstin Williams, Petra C.F. Oyston, Nick Dorrell, Shu-Rui Li, Richard W. Titball, Brendan W. Wren

Journal:

FEMS Microbiology Letters

Year:

2000

Language:

english

File:

PDF, 274 KB

english, 2000

40

The failure of different strains of Yersinia pestis to produce lipopolysaccharide O-antigen under different growth conditions is due to mutations in the O-antigen gene cluster

Joann L. Prior, Julian Parkhill, Paul G. Hitchen, Karen L. Mungall, Kim Stevens, Howard R. Morris, Andrew J. Reason, Petra C.F. Oyston, Anne Dell, Brendan W. Wren, Richard W. Titball

Journal:

FEMS Microbiology Letters

Year:

2001

Language:

english

File:

PDF, 214 KB

english, 2001

41

Microbial genome analysis: insights into virulence, host adaptation and evolution

Wren, Brendan W.

Journal:

Nature Reviews Genetics

Year:

2000

Language:

english

File:

PDF, 732 KB

english, 2000

42

Bacterial pathogenomics

Pallen, Mark J., Wren, Brendan W.

Journal:

Year:

2007

Language:

english

File:

PDF, 827 KB

english, 2007

43

Deciphering tsetse's secret partner

Wren, Brendan W.

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 190 KB

english, 2002

44

Invertebrates as a source of emerging human pathogens

Waterfield, Nicholas R., Wren, Brendan W., ffrench-Constant, Richard H.

Journal:

Nature Reviews Microbiology

Year:

2004

Language:

english

File:

PDF, 307 KB

english, 2004

45

Protein glycosylation in bacterial mucosal pathogens

Szymanski, Christine M., Wren, Brendan W.

Journal:

Nature Reviews Microbiology

Year:

2005

Language:

english

File:

PDF, 382 KB

english, 2005

46

The Yersiniae — a model genus to study the rapid evolution of bacterial pathogens

Wren, Brendan W.

Journal:

Nature Reviews Microbiology

Year:

2003

Language:

english

File:

PDF, 1.02 MB

english, 2003

47

Mucosal Immunization with a Urease B DNA Vaccine Induces Innate and Cellular Immune Responses Against Helicobacter pylori

Caterina Hatzifoti, Yvonne Roussel, Andrew G. Harris, Brendan W. Wren, John W. Morrow, Mona Bajaj-Elliott

Journal:

Year:

2006

Language:

english

File:

PDF, 191 KB

english, 2006

48

TheCampylobacter jejuniNCTC11168 capsule prevents excessive cytokine production by dendritic cells

Anna Rose, Emily Kay, Brendan W. Wren, Margaret J. Dallman

Journal:

Medical Microbiology and Immunology

Year:

2012

Language:

english

File:

PDF, 410 KB

english, 2012

49

The Campylobacter jejuni glycome

Andrey V. Karlyshev, Julian M. Ketley, Brendan W. Wren

Journal:

FEMS Microbiology Reviews

Year:

2005

Language:

english

File:

PDF, 586 KB

english, 2005

50

Effect of chicken meat environment on gene expression of Campylobacter jejuni and its relevance to survival in food

Małgorzata Ligowska, Marianne Thorup Cohn, Richard A. Stabler, Brendan W. Wren, Lone Brøndsted

Journal:

International Journal of Food Microbiology

Year:

2011

Language:

english

File:

PDF, 196 KB

english, 2011